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Year : 1999  |  Volume : 2  |  Issue : 2  |  Page : 66-72

Antioxidants in neonatal sytemic diseases


Department of Paediatrics. Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

Correspondence Address:
K I Airede
Department of Paediatrics. Usmanu Danfodiyo University Teaching Hospital, Sokoto
Nigeria
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Free radicals are highly reactive, unstable substances which are produced during normal metabolism in the human body. These su6stances such as superoxide dismutase, catalase, ceruloplasmin, glutathione peroxidase, glutathione reductase and micronutrient trace metals, are·taking up significant contributions to causation of disease with important sequelae. The newborn infant bears the brunt of these processes if their antioxidant capacity is deficient or diminished. This article attempts to emphasise on recent information and rationale behind free radical injuries to tissues/ systems within the body. The prospects for preventing and potential therapeutic interventions of such damages will also be reached


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