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CASE REPORT
Year : 2004  |  Volume : 7  |  Issue : 3  |  Page : 101-105

Infections and thrombocytopenia in chronic idiopathic thrombocytopenic purpura (itp)- A case report


Department of Haematology and Blood Transfusion, College of Medical Sciences, University of Benin, Benin - City, Edo State, Nigeria

Correspondence Address:
NKD Halim
Department of Haematology and Blood Transfusion, College of Medical Sciences, University of Benin, Benin - City, Edo State
Nigeria
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This is a case report to study the association between episodes of thrombocytopenia and bacterial infections in a patient with chronic idiopathic thrombocytopenic purpura ( IT P ).The case was a 31 year old female patient , with a history of chronic ecchymosis , melaena stool and menorrhagia, who presented at the female Medical Ward and Pathology Laboratory of the University of Benin Teaching Hospital . Her sputum culture yielded gram positive cocci and gram negative bacilli , on three occasions, simultaneously with low platelet count and thrombocytopenia in the blood film . The platelet counts improved when the infectious agent was eliminated with antibiotics. We conclude that the presence of bacterial infection and a low platelet count , with subsequent improvement of the platelet count following antibiotic therapy suggest an association between bacterial infection and thror;1bocytopenia in chronic ITP. This is the first reported case in this environment. There is a need to identify and vigorously treat bacterial infection with antibiotics in \..ITP patient s prior to steroid usage.


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