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Year : 2009  |  Volume : 12  |  Issue : 1  |  Page : 13-18

Clinical indicators of HIV infection in under-five children with diarrhoea in a esource-limited setting

Department of Paediatrics, Aminu Kano Teaching Hospital, Kano State, Nigeria

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F Hassan-Hanga
Department of Paediatric, Aminu Kano Teaching Hospital, Kano State
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Background: Children are most vulnerable to human immunodeficiency virus infection but in sub-Saharan African countries they are diagnosed late because paediatric human immunodeficiency virus diagnostic facilities are limited. Methods: Prospective study of 400 under-five children with diarrhoea in a hospital sitting. Results: Twenty six children (6.5%) were human immunodeficiency virus positive. Compared to the children who were human immunodeficiency virus negative, those who were positive had higher proportions of patients with acute diarrhoea (77%, p<0.002); recurrent diarrhoea (54%, p<0.001), chronic diarrhoea (p<0.002), caugh (73%, p<0.001); weight loss (18%, p<0.001) and delayed/developmental milestone loss (38%, p<0.001). Conclusions: In resource limited settings cough, wasting or developmental delay associated with chronic diarrhoea may be used as indicators for human immunodeficiency virus screening in under-five children.

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