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ORIGINAL ARTICLE
Year : 2006  |  Volume : 9  |  Issue : 3  |  Page : 104-107

A comparison of diazepam with promethazine as an oral premedicant for children


Department of Anaesthesia, University of Nigeria Teaching Hospital, Enugu, Nigeria

Correspondence Address:
PUN Nze
Department of Anaesthesia , University of Nigeria Teaching Hospital , Enugu
Nigeria
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Objectives: To compare the effectiveness of Diazepam and Promethazine for oral premedication In children undergoing tonsillectomy and/or adenoidectomy under general anaesthesia. Method/Design: The effect of oral premedication was Investigated In a double blind, randomized trial in 85 children. The children were randomly allocated to one of three group! . Group 1 received promethazine and placebo. Group 2 received diazepam and placebo while group 3 received two placebo preparations. Sedation scores for the 3 groups were com pare.: before leaving the ward for the operation room and also In the recovery room. Other parameters such as Induction scores , compliance and sedation scores were also compared. Results: Following premedication with diazepam none of the patients was anxious, crying or distressed on leaving the ward compared with 2!28 In the promethazlen group and 5/28 in the placebo group. More patients (25/28; 89%) were calm and quiet on arrival in the operatinfl room following diazepam than following promethazine, (12/28; 43%). Conclusion: Diazepam compared with promethazine Is a more effective oral premedicant for children


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