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Year : 2013  |  Volume : 16  |  Issue : 3  |  Page : 133-135

Juvenile ocular myasthenia gravis in association with thymolipoma

Department of Pathology, Indira Gandhi Medical College, Shimla, India

Correspondence Address:
Kavita Mardi
12-A, Type V Quarters, IAS Colony, Kasumpti, Shimla, H.P
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DOI: 10.4103/1118-8561.121928

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Thymolipomas are uncommon tumors of anterior mediastinum. Their association with juvenile ocular myasthenia gravis is extremely rare. A 14-year-old boy presented with ptosis of 2 years and left-sided diplopia of 19 months duration. On examination external ophthalmoplegia and ptosis were present. Generalized muscle weakness was absent. On a neostigmine challenge test, the boy showed improvement in symptoms after 20 minutes of neostigmine injection. Anticholinesterase antibodies and antinuclear antibodies were negative. Chest CT revealed a soft tissue mass in the anterior mediastinum. Histopathological examination of the excised mass was diagnostic of thymolipoma.

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