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Year : 2013  |  Volume : 16  |  Issue : 4  |  Page : 168-170

Xanthogranulomatous cholecystitis: Report of a case with coexistent adenocarcinoma

1 Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India
2 National Institute of Pathology, ICMR, Safdurjung Hospital Campus, New Delhi, India

Correspondence Address:
Zeeba S Jairajpuri
Department of Pathology, Hamdard Institute of Medical Sciences and Research, Hamdard Nagar, Jamia Hamdard, New Delhi - 110 062
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DOI: 10.4103/1118-8561.125569

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Xanthogranulomatous cholecystitis (XGC) is an uncommon benign focal or diffuse destructive inflammatory disease of the gallbladder. Pre-operative and intra-operative diagnosis is difficult and it often mimics a gallbladder carcinoma (GBC). This diagnostic dilemma caused by equivocal imaging studies and intra-operative findings can at times be aggravated by a histological picture which mimics a neoplasm. Apart from occasionally presenting as an infiltrating mass lesion with adjacent organ invasion like a malignant neoplasm, XGC can also infrequently be associated with GBC. Lack of awareness that both XGC and carcinoma can co-exist as well as interpreter's inexperience may lead to a missed diagnosis. We present a case of to illustrate this coexistence and conclude that XGC and carcinoma of the gall bladder may co-exist and present a diagnostic dilemma. We recommend increased awareness of this knowledge among radiologists, surgeons and pathologists to raise its awareness.

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