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Year : 2014  |  Volume : 17  |  Issue : 4  |  Page : 125-127

Comparison of echocardiographic parameters among patients with pulmonary hypertension treated with statin and those without

Department of Medicine, Division of Cardiology, University of Dammam, Dammam, Saudi Arabia

Correspondence Address:
Mohammed Almansori
Department of Medicine, Division of Cardiology, University of Dammam, P. O. Box 12875, Dammam 31483
Saudi Arabia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1118-8561.146813

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Introduction: Pulmonary hypertension is a progressive disease where endothelial dysfunction plays an important role in its etiology. Statins have been considered a therapeutic option for pulmonary hypertension due to their pleiotropic effects. Materials and Methods: We investigated the association between statin use and echocardiographic parameters in 73 patients with pulmonary hypertension (23 patients were on statin and 50 patients were not taking statin). Results: Our study showed no association between statin use and different echocardiographic parameters used to evaluation pulmonary hypertension though there was a trend toward less right ventricular dilatation favoring the statin group (25.20 ± 14.7 mm vs. 29.7 ± 9.5) with a P = 0.052. Conclusion: We observed noassociation between statin use and echocardiographic findings in patients with pulmonary hypertension. A larger scale studies are need to confirm our findings.

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